000			03304cam a22003378i 4500
001			21551397
003			BT-SaRUSC
005			20221219145114.0
008			200604s2022 nju b 001 0 eng
010			_a 2020025620
020			_a9781119512851 _q(paperback)
020			_z9781119512820 _q(adobe pdf)
020			_z9781119512844 _q(epub)
040			_aDLC _beng _erda _cDLC _dDLC
042			_apcc
050	0	0	_aQH491 _b.S6 2022
082	0	0	_a572.8 _223
100	1		_aSlack, J. M. W. _q(Jonathan Michael Wyndham), _d1949- _eauthor.
245	1	0	_aEssential developmental biology / _cJonathan M.W. Slack, University of Bath, Bath, United Kingdom, Leslie Dale, University College London, London, United Kingdom.
250			_aFourth edition.
263			_a2111
300			_apages cm
500			_aRevised edition of: Essential developmental biology / Jonathan M.W. Slack. 3rd ed. 2013.
504			_aIncludes bibliographical references and index.
520			_a"This book presents the basic concepts and facts relating to the developmental biology of animals. It is designed as a core text for undergraduate courses from the first to the fourth year, and also for first year graduate students. It is suitable for both biologically based and medically oriented courses. A basic knowledge of cell and molecular biology is assumed, but no prior knowledge of development, animal structure, or histology should be necessary For this, the fourth edition, the work has two authors. Leslie Dale runs the developmental biology teaching at University College London and has brought his invaluable teaching experience as well as his daily contact with cutting edge research to complement the expertise of the senior author, Jonathan Slack. Two technical advances in particular have been incorporated into the text. The first is single cell transcriptome sequencing which provides a completely new way to observe developmental fate and commitment at a molecular level. The second is CRISPR/Cas9, and other methods for targeted genetic manipulation, that have hugely extended the range of what can be done. The book is arranged in four sections and the order of topics is intended to represent a logical progression. The first section introduces the basic concepts and techniques. Chapter 2 "How Development Works" is intended as a very brief summary of developmental mechanisms suitable for introductory lectures. We have moved the biochemistry of signaling systems, formerly in the appendix, into Chapter 4. So now the theoretical concepts of experimental embryology are presented together with the molecular pathways that underlie them. Section 1 also contains a new chapter on "Cells into Tissues" dealing with the fundamentals of morphogenesis and the underpinning role of cell contacts and the cytoskeleton. In other works, this topic is often fragmented among many individual examples and loses its coherence"--
541			_aPurchased from trinkets and bookworld _d15.12.22 _e25430-A19796 25431-A19797 _hNu.13250
650		0	_aDevelopmental biology _vLaboratory manuals.
700	1		_aDale, Leslie, _eauthor.
776	0	8	_iOnline version: _aSlack, Jonathan M. W., _tEssential developmental biology _bFourth edition. _dHoboken : Wiley, 2022. _z9781119512820 _w(DLC) 2020025621
942			_2ddc _cBK
999			_c18997 _d18997