ENZYMES: Catalysis, Kinetics and Mechanisms (Record no. 17680)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05173nam a22005175i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 978-981-13-0785-0 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20200712165718.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 181111s2018 si | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9789811307850 |
| -- | 978-981-13-0785-0 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-981-13-0785-0 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QD431-431.7 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSBZ |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SCI007000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | PSB |
| Source | thema |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 572.6 |
| Edition number | 23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Punekar, N.S. |
| Relator term | author. |
| Relator code | aut |
| -- | http://id.loc.gov/vocabulary/relators/aut |
| 245 10 - TITLE STATEMENT | |
| Title | ENZYMES: Catalysis, Kinetics and Mechanisms |
| Medium | [electronic resource] / |
| Statement of responsibility, etc | by N.S. Punekar. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. 2018. |
| 264 #1 - | |
| -- | Singapore : |
| -- | Springer Singapore : |
| -- | Imprint: Springer, |
| -- | 2018. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XXIII, 562 p. 263 illus., 76 illus. in color. |
| Other physical details | online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | text file |
| -- | |
| -- | rda |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Part I: Enzyme catalysis - a perspective -- Enzymes -Their place in Biology -- Enzymes - Historical aspects -- Exploiting enzymes – Technology -- On enzyme nomenclature and classification -- Hallmarks of an enzyme catalyst -- Origins of enzyme catalytic power -- Origins of enzyme catalytic power -- Which enzyme uses what trick? Some remarks -- Structure and catalysis: Conformational flexibility and protein motion -- Part II: Enzyme kinetic practice and measurements -- Chemical kinetics – Fundamentals -- Concepts of equilibrium and steady-state -- ES complex and pre-steady-state kinetics -- Principles of enzyme assays -- Good kinetic practices -- Quantification of catalysis and measures of enzyme purity -- Henri-Michaelis-Menten equation -- More complex rate expressions -- Enzyme kinetic data - Collection and analysis -- Part III: Elucidation of Kinetic mechanisms -- Approaches to kinetic mechanism – Overview -- Analysis of initial velocity patterns -- Enzyme inhibition analyses -- Irreversible inhibitions -- Reversible inhibitions -- Alternate substrate (product) interactions -- pH Studies with enzymes -- Isotopes in enzymology -- Isotope exchanges at equilibrium -- Isotope effects in enzymology -- From kinetic data to mechanism and back -- Part IV: Chemical mechanisms and catalysis -- Chemical reactivity and molecular interactions -- Acid-base chemistry and catalysis -- Nucleophilic catalysis and covalent reaction intermediates -- Phosphoryl group chemistry and importance of ATP -- Enzymatic oxidation-reduction reactions -- Carboxylations and decarboxylations -- Electrophilic catalysis and amino acid transformations -- Integrating kinetic and chemical mechanisms – A synthesis -- Part V: Frontiers in enzymology -- Regulation of enzyme activity -- In vitro versus in vivo - Concept and consequences -- Future of enzymology – An appraisal -- Closure - Whither Enzymology. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | This enzymology textbook for graduate and advanced undergraduate students covers the syllabi of most universities where this subject is regularly taught. It focuses on the synchrony between the two broad mechanistic facets of enzymology: the chemical and the kinetic, and also highlights the synergy between enzyme structure and mechanism. Designed for self-study, it explains how to design enzyme experiments and subsequently analyze the data collected. The book is divided into five major sections: 1] Introduction to enzymes, 2] Practical aspects, 3] Kinetic Mechanisms, 4] Chemical Mechanisms, and 5] Enzymology Frontiers. Individual concepts are treated as stand-alone chapters; readers can explore any single concept with minimal cross-referencing to the rest of the book. Further, complex approaches requiring specialized techniques and involved experimentation (beyond the reach of an average laboratory) are covered in theory with suitable references to guide readers. The book provides students, researchers and academics in the broad area of biology with a sound theoretical and practical knowledge of enzymes. It also caters to those who do not have a practicing enzymologist to teach them the subject. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Enzymology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Proteins . |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedical engineering. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Microbiology. |
| 650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Enzymology. |
| -- | http://scigraph.springernature.com/things/product-market-codes/L14070 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Protein-Ligand Interactions. |
| -- | http://scigraph.springernature.com/things/product-market-codes/L14060 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Biomedical Engineering/Biotechnology. |
| -- | http://scigraph.springernature.com/things/product-market-codes/B24000 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Applied Microbiology. |
| -- | http://scigraph.springernature.com/things/product-market-codes/C12010 |
| 650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Protein Structure. |
| -- | http://scigraph.springernature.com/things/product-market-codes/L14050 |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9789811307843 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Printed edition: |
| International Standard Book Number | 9789811307867 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1007/978-981-13-0785-0">https://doi.org/10.1007/978-981-13-0785-0</a> |
| 912 ## - | |
| -- | ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | |
No items available.